Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?

Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.

At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 1 - 10 of 74 |
Senior Scientist, Bioanalytical - Immunogenicity
Cambridge, Massachusetts
Talent Acquisition Partner: Jeannine Ripley Hiring Manager: Guodong Zhang Overview The Bioanalytical Sciences group at Alnylam is seeking a highly motivated Senior Scientist, specializing in designing and conducting immunogenicity assessmen...
8h
| Job Type | Full Time |
Sr. Manager, IT Project Management
Cambridge, Massachusetts
Overview: The Portfolio and Project Manager will play a key role within the IT PMO, providing strategic oversight and operational excellence across the IT portfolio. This role is responsible not only for managing and delivering critical pro...
8h
| Job Type | Full Time |
Business Account Executive, TTR - Detroit North
Cambridge, Massachusetts
Overview We are looking for experienced Business Account Executives (BAEs) with specialty sales experience to promote AMVUTTRA. hATTR patients often spend years undiagnosed and misdiagnosed. This is an amazing opportunity to educate and enh...
1d
| Job Type | Full Time |
Principal Scientist, Advanced In Vitro Platforms
Cambridge, Massachusetts
Overview We are seeking an accomplished and motivated Principal Scientist to lead innovation in advanced in vitro modeling to enable RNAi discovery and development. In this role, you will be responsible for designing, validating, and implem...
1d
| Job Type | Full Time |
Manufacturing Suite Coordinator
Cambridge, Massachusetts
Overview The Suite Coordinator is accountable for operational readiness to support schedule adherence, smooth handoff of documentation and process steps with other departments, and completion of follow up actions on safety initiatives. Repo...
1d
| Job Type | Full Time |
Director, Commercial Global Compensation
Cambridge, Massachusetts
Overview: We are seeking a Director, Global Compensation, to join our Total Rewards and HR Innovation and Analytics team and make a significant impact in a fast-growing business. We seek an individual capable of providing Global Compensatio...
2d
| Job Type | Full Time |
Cambridge, Massachusetts
Sr Manager, Invoice to Pay Position Summary: The Senior Manager, Accounts Payable will be responsible for managing the operational functions and activities of a fast-paced, Accounts Payable Department ensuring work requirements are performe...
2d
| Job Type | Full Time |
Vice President of Financial Planning and Analysis
Cambridge, Massachusetts
Overview: We're looking for a strategic and experiencedVice President of Finance to lead the financial planning and analysis function supporting our Research & Development (R&D) Tech Ops and Quality (TOQ) teams. This role will partner with ...
2d
| Job Type | Full Time |
Cambridge, Massachusetts
Overview: The successful pathologist candidate will join an experienced team of pathologists providing discovery and development support on a strong pipeline of programs covering a large breadth of disease areas. In addition to routine path...
2d
| Job Type | Full Time |
Principal Associate Scientist, RNAi Discovery
Cambridge, Massachusetts
Overview The Research Department at Alnylam Pharmaceuticals is seeking a Principal Associate Scientist to join our High Throughput In Vitro team within the RNAi Discovery group. This dynamic, interdisciplinary team drives the discovery and ...
2d
| Job Type | Full Time |