Lab Manager Flow Cytometry

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world's leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world's deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. These values are grounded in and expressed through the principles of diversity, equity and inclusion. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an anti-racist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, anti-racism and inclusion.

The Flow Cytometry Services Manager is an integral leadership position within Cellular Therapeutics Program (CTP). CTP is comprised of four functional groups with responsibility for the production and management of clinical cellular products for patient treatment: Apheresis Unit at Fred Hutch, Cellular Therapy Laboratory (CTL), Quality Assurance (QA), and Cellular Therapy Services (CTS).

The Flow Cytometry Services Manager will assist Medical and Scientific Directors with development, implementation and management of new and updated clinical flow cytometry assays.

Job responsibilities include operational and technical oversight of preparation of biological samples and data analysis of flow cytometry testing, troubleshooting and maintenance of flow cytometers and creation and maintenance of lab protocols and lab workflows to ensure flow cytometry testing quality, patient safety, efficiency and compliance with standards, regulations and guidelines.

Demonstrate leadership in developing and implementing operational and strategic initiatives for Fred Hutch Flow Cytometry Services.
• Collaborate with the Medical and Scientific Directors on design, validation and implementation of clinical flow assays.
• Responsible for clinical software validation and implementation, as applicable.
• Responsible for flow cytometry service operations:
  • Manage daily flow sorting operation
  • Daily technical and operational support of flow cytometry assays, such as instrument issues and process improvements.
  • Data preview and reporting.
  • Oversee quality control and proficiency testing.
  • Monitor instrument performance and coordinate the maintenance.
• Participate in clinical trials assays set-up and management, contracting and service agreement negotiation.
• Develop new flow cytometry panels on conventional flow cytometry instruments and spectral flow cytometry.
• Collaborate with the clinical and administrative leadership on clinical trial cost accounting, budgeting, and billing.
• Play a vital role in coordinating service activities, maintaining compliance, and fostering a culture of excellence within the team.
• Maintain professional and technical knowledge by attending educational workshops; reviewing professional publications; establishing personal networks; participating in professional societies.
• Supervise and/or mentor staff in flow cytometry service and provide guidance, support, and training to ensure efficient effective performance. Participate in assessing staff competency.

Required:

• Have earned a bachelor's degree in a chemical, biological, clinical or medical laboratory science, or medical technology from an accredited institution or meet other education requirements under 42 CFR 493.1449
• Minimum 4 years' post-degree experience with bachelor's degree in clinical flow service and flow assay development & validation OR minimum 2 years' post-degree experience in clinical flow service and flow assay development & validation with master's degree or higher
• At least 2 years' laboratory leadership experience working with personnel and projects in CLIA clinical laboratory. Knowledge and/or experience with clinical genomic applications is optional but favored.
• Practical in-depth expertise in flow cytometry in CLIA clinical laboratory.
• Proven experience working effectively with clinicians, administrators and researchers in a multi-disciplinary environment and across organizational lines to achieve excellent outcomes.
• Experience with process and equipment validations. Working knowledge of laboratory equipment management.
• Experience in multiparameter diagnostic flow cytometry, cell sorting for diagnostic applications and antibody-based cell enumeration (e.g. CD34) assays.
• Experience in supporting clinical trials and clinical laboratory Quality Management System is a strong plus.
• Strong leadership abilities.
• Ability to understand and interpret complex written materials and technical reports.
• An effective planner with strong skills in scheduling and organizing work processes.
• Self-motivated, detail oriented, highly organized and able to multitask and work within a rapidly changing environment
• Ability to alternate between being a leader and an individual contributor.

Preferred:

• Master's degree or higher
• 7 years or more of total experience is preferred.
• ASCP certification in either Medical Laboratory Science general or flow certification.
• Knowledge and/or experience with clinical genomics is optional but a plus for potential lab expansion.
• Experience in a large, complex ambulatory cancer center is desired. Ideally there will be experience working in clinical CLIA laboratory, academic and research environment

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

The annual base salary range for this position is from $112,924 to $178,464 and pay offered will be based on experience and qualifications.

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, tuition reimbursement, paid vacation (12-22 days per year), paid sick leave (12-25 days per year), paid holidays (13 days per year), paid parental leave (up to 4 weeks), and partially paid sabbatical leave (up to 6 months).

This position may be eligible for relocation assistance.