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Postdoctoral Fellow - RNA Delivery, Yen/Fan/Emani Labs

Genentech
United States, California, South San Francisco
Dec 03, 2025
The Position

We advance science so that we all have more time with the people we love.

A postdoctoral fellow position is available for a highly motivated and independent candidate to join the laboratory of Dr. Chun-Wan Yen and Dr. Yuchen Fan in the Department of Synthetic Molecule Pharmaceutical Science (SMPS) at Genentech and Dr. Maheswara Reddy Emani in Biochemical Cellular Pharmacology (BCP) department. The position focuses on drug delivery development, with an emphasis on nanomedicine and lipid nanoparticle (LNP) enabled RNA delivery. We are committed to advancing the understanding of structure-activity relationships between LNP design and biological performance.

This postdoctoral role offers an opportunity to investigate the innate immune response to RNA delivery. The fellow will work within a joint research environment between SMPS and BCP departments, contributing to the development of ML/AI models for LNP formulation and characterization, as well as the development of in vitro systems.

The Opportunity:

  • This position will also work closely with mentors in immunology discovery and AI Machine Learning teams to establish a predictive model between RNA/lipid nanoparticle and immune stimulations.

  • As a member of the joint departments, you will have cross-functional collaborations.

  • Join the Genentech Postdoctoral Program, which offers outstanding training and mentorship, opportunities to present work internally and externally, and a strong focus on career development.

Who You Are:

  • Ph.D. in chemistry, biochemistry, biomedical engineering, or a related discipline

  • Demonstrated strong research track record, including first-author publications, and a passion for solving scientific problems through creative approaches

  • Excellent communication and presentation skills

Preferred Qualifications:

  • Familiarity with relevant experimental techniques, including hands-on experience with cell culture, in vitro assay development, and knowledge of LNP workflows

  • Experience with machine learning or data mining is a plus

For information about the Yen lab at Genentech, please go to:

https://www.gene.com/scientists/our-scientists/chun-wan-yen

The expected salary range for this position based on the primary location of South San Francisco California is $98,000 to $104,500. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for the benefits detailed at the link provided below.

Benefits

Relocation benefits are available for this job posting.

Postdoc Program

Elevate your research career to new heights with Genetech's Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions.

The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader.

The Genentech Postdoc Program provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to Genentech Postdoctoral Program and unlock your full potential!

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Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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