Research Postdoctoral Fellow - Human Synaptic Physiology

A Brief Overview

Assume responsibility for an on-going, innovative research project as a Postdoctoral Fellow at CHOP. Our postdoc experience will broaden your skillset, scientific background, and research capabilities. Dr. Stewart Anderson has a postdoctoral fellowship in live imaging of synaptic activity using human stem cell-derived neurons.

CHOP's Commitment to Diversity, Equity, and Inclusion
CHOP is committed to building an inclusive culture where employees feel a sense of belonging, connection, and community within their workplace. We are a team dedicated to fostering an environment that allows for all to be their authentic selves. We are focused on attracting, cultivating, and retaining diverse talent who can help us deliver on our mission to be a world leader in the advancement of healthcare for children.

We strongly encourage all candidates of diverse backgrounds and lived experiences to apply.

About the Laboratory

We are using human stem cell derived excitatory and inhibitory neurons, astrocytes, microglia, and neurovascular-like cells in mono-and mixed carpet cultures, as well as organoid differentiations, as tools for the study of gene-gene and gene-environment interactions in neuropsychiatric disease. Illnesses of particular interest include schizophrenia and autism, with emphasis on mitochondrial influences on symptom penetrance and treatment. For this position the focus is on live imaging of presynaptic vesicle cycling and glutamate release in human stem cell derived neurons from patients with autism and schizophrenia. To be considered applicants must have substantial experience in conducting whole cell electrophysiological recordings and/or live imaging of neuronal activity. Experience in human stem cell culture, manipulation, and differentiation is preferred but not required.

Responsibilities

• Participate in project planning, recording, and evaluation of data.

• Conduct independent scholarly research, developing new methods and protocols under the guidance of a mentor (principal investigator).

• Acquire technical, lab management, and grant writing skills.

• Participate in seminars, lectures, poster sessions, national presentations, and professional workshops.

• Supervise junior lab members.

• Assist with other research projects as needed.

Education

• Required: Doctorate