Post Doctoral Fellow - Department of Cancer Biology - Lab of Dr. Christine Eischen

Thomas Jefferson University & Jefferson Health
United States, Pennsylvania, Philadelphia
951 Locust Street (Show on map)
Dec 18, 2024
Job Details The Eischen laboratory needs a highly motivated postdoctoral fellow. Postdoctoral fellows should be interested in genetic, molecular, or biochemical mechanisms of tumor development and survival. The laboratory utilizes genetically engineered mouse models, primary cell culture, retroviral gene transfer technologies, protein purification, genomics, microscopy, computational biology, and patient sample analysis, to answer biological questions related to tumor initiation and survival. We published in high profile journals (e.g., Nature Comm. 2017 and 2020, J. Clinical Invest. 2017, Clinical Can. Res., 2017, Cancer Res. 2019, and Leukemia 2020). Project 1 focuses on BCL2 family members and their roles in B cell lymphoma survival and drug resistance. This project involves biochemical, cellular, and mouse modeling approaches to characterize various BCL2 family members and ways to capitalize on their targeting for the treatment of lymphomas and overcoming resistance to treatments. Project 2 is focused on non-coding RNA in carcinomas (lung, breast, etc.) and lymphomas and their contribution to its development, growth, and progression. Mouse models, cellular, computational biology, and various other approaches to evaluate non-coding RNA and their targets are utilized. Job Description PhD or M.D. required. Applicants must be skilled in cancer biology techniques (e.g., biochemistry, cell culture, mouse models, flow cytometry, etc.). PhD or M.D. required. Applicants must be skilled in cancer biology techniques (e.g., biochemistry, cell culture, mouse models, flow cytometry, etc.). Work Shift Workday Day (United States of America) Worker Sub Type Regular Primary Location Address 951 Locust Street, Philadelphia, Pennsylvania, United States of America Nationally ranked, Jefferson, which is principally located in the greater Philadelphia region, Lehigh Valley and Northeastern Pennsylvania and southern New Jersey, is reimagining health care and higher education to create unparalleled value. Jefferson is more than 65,000 people strong, dedicated to providing the highest-quality, compassionate clinical care for patients; making our communities healthier and stronger; preparing tomorrow's professional leaders for 21st-century careers; and creating new knowledge through basic/programmatic, clinical and applied research. Thomas Jefferson University, home of Sidney Kimmel Medical College, Jefferson College of Nursing, and the Kanbar College of Design, Engineering and Commerce, dates back to 1824 and today comprises 10 colleges and three schools offering 200+ undergraduate and graduate programs to more than 8,300 students. Jefferson Health, nationally ranked as one of the top 15 not-for-profit health care systems in the country and the largest provider in the Philadelphia and Lehigh Valley areas, serves patients through millions of encounters each year at 32 hospitals campuses and more than 700 outpatient and urgent care locations throughout the region. Jefferson Health Plans is a not-for-profit managed health care organization providing a broad range of health coverage options in Pennsylvania and New Jersey for more than 35 years. Jefferson is committed to providing equal educational and employment opportunities for all persons without regard to age, race, color, religion, creed, sexual orientation, gender, gender identity, marital status, pregnancy, national origin, ancestry, citizenship, military status, veteran status, handicap or disability or any other protected group or status.